"You never know what is going to happen at Old Trafford and Old Trafford can be a graveyard for teams," Gary Neville said on The Gary Neville Podcast.
"Even with the way Manchester United are at the moment, you have to regard that as a massive match and a big game.
"Teams have won at Old Trafford that have been in the bottom half of the table, but teams in the top half of the table have gone there and struggled.
"Liverpool famously in the last month or two have lost an FA Cup quarter-final there and they drew in the league and that was probably the start of Liverpool's downfall in terms of where they are now [compared to where they were then], in terms of dropping out of the title race and getting knocked out of the FA Cup.
"You can never underestimate a game at Old Trafford. If you look at a collection of matches it can be overwhelming, but if you look at the form that Arsenal have been in and the defensive stability they have had, it's not because of team errors [that they conceded two goals against Spurs].
